Deados are the main antagonists of R.I.P.D.. They are human spirits who have died but could not or refused to move on the the afterlife. They return to Earth as chaotic ghosts, causing disruptions in the world. It is the responsibility of the R.I.P.D to capture deados and send them to the afterlife. If they refuse to cooperate with R.I.P.D officers, they are erased from the cosmos forever with Soul-Killer bullets.

Deados possess the same powers as R.I.P.D officers. They are immortal, cannot be harmed except by Soul-Killers and are very strong. Some have been seen to jump great heights and walk on walls.